What is this medication?
Angiotensin-Converting Enzyme (ACE) Inhibitor; Antihypertensive
Lisinopril, Prinivil/Zestril is officially indicated for heart failure, hypertension, ST-elevation myocardial infarction.
How does this medication work?
Lisinopril, Prinivil/Zestril is a competitive inhibitor of angiotensin-converting enzyme (ACE); prevents conversion of angiotensin I to angiotensin II, a potent vasoconstrictor; results in lower levels of angiotensin II which causes an increase in plasma renin activity and a reduction in aldosterone secretion; a CNS mechanism may also be involved in hypotensive effect as angiotensin II increases adrenergic outflow from CNS; vasoactive kallikreins may be decreased in conversion to active hormones by ACE inhibitors, thus reducing blood pressure.
How should I take this medication?
Usual (Oral): 2.5mg to 10mg once daily.
How to Take: Can take with or without food.
What should I watch for while using this medication?
Before starting Lisinopril, Prinivil/Zestril make sure your physician is aware of any allergies and medications you currently take. Lisinopril, Prinivil/Zestril have rarely been associated with angioedema, cholestatic jaundice, hyperkalemia, hypotension/syncope and deteriorating renal function.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Hypotension, dizziness, increased serum creatinine, increased blood urea nitrogen.
Note this is not a complete list of side effects for Lisinopril, Prinivil, Zestril only common ones.
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