What is this medication?
Tenofovir Disoproxil Fumarate, Viread
Antihepadnaviral, Reverse Transcriptase Inhibitor, Nucleotide (Anti-HBV); Antiretroviral, Reverse Transcriptase Inhibitor, Nucleotide (Anti-HIV)
“Alert: Black Box Warning
Post-treatment acute exacerbation of hepatitis B:
Severe acute exacerbations of hepatitis B virus (HBV) have been reported in HBV-infected patients who have discontinued anti-hepatitis B therapy. Hepatic function should be monitored closely with both clinical and laboratory follow-up for at least several months in HBV-infected patients who discontinue anti-hepatitis B therapy.”
How does this medication work?
Tenofovir Disoproxil Fumarate, Viread is hydrolyzed to tenofovir which is phosphorylated to tenofovir diphosphate. Tenofovir diphosphate inhibits the activity of HIV-1 reverse transcriptase by competing with the natural substrate, deoxyadenosine 5′-triphosphate, and thereby inhibits hepatitis B virus replication.
How should I take this medication?
Usual (Oral): One tablet daily.
How to Take: Can take with or without food.
What should I watch for while using this medication?
Before starting Tenofovir Disoproxil Fumarate, Viread make sure your physician is aware of any allergies or medications you currently take. There are risks associated with taking Tenofovir disoproxil fumarate such as a decrease in bone mineral density, immune reconstitution syndrome (i.e. Graves’ disease, polymyositis, Guillain-Barré syndrome), lactic acidosis/hepatomegaly, osteomalacia and renal and hepatic dysfunction.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Insomnia, headache, pain, dizziness, depression, skin rash, pruritis, hypercholesterolemia, abdominal pain, nausea, vomiting, diarrhea, fever.
Note this is not a complete list of side effects for Tenofovir Disoproxil Fumarate, Viread only common ones.
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