What is this medication?
Scopolamine, Transderm Scop (US)/Buscopan (CDN)
Brand Name US: Transderm Scop
Canadian Equivalent: Buscopan
Scopolamine base: Transdermal: Prevention of nausea/vomiting associated with motion sickness and recovery from anesthesia and surgery
Scopolamine hydrobromide [Canadian product]: Injection: Adjunct to anesthesia to produce sedation and amnesia
Scopolamine butylbromide [Canadian product]: Oral/injection: Treatment of smooth muscle spasm of the genitourinary or GI tract; injection may also be used prior to radiological/diagnostic procedures to prevent spasm
How does this medication work?
Scopolamine, Transderm Scop/Buscopan blocks the action of acetylcholine at parasympathetic sites in smooth muscle, secretory glands, and the CNS. This increases cardiac output, decreased mucosal secretions, antagonizes histamine and serotonin, causes blockade of muscarinic receptors at the cardiac SA-node and is parasympatholytic.
How should I take this medication?
Scopolamine base: Transdermal patch: Apply 1 patch to hairless area behind the ear at least 4 hours prior to exposure and every 3 days as needed
Scopolamine hydrobromide: IM, IV, SubQ: 0.3 to 0.6 mg 3 to 4 times/day
Scopolamine butylbromide: Oral: 10 to 20 mg/day; prolonged therapy: 10 mg 3 to 5 times/day; maximum: 60 mg/day. IM, IV, SubQ: 10 to 20 mg; maximum: 100 mg/day
How to Take: Apply transdermal patch to hairless area of skin behind the ear. Wear only one patch at a time; remove first patch and apply new patch behind the other ear. When used postoperatively for nausea/vomiting, the patch should be removed 24 hours after surgery. If patch becomes displaced, discard and apply a new patch. Once removed, fold the used patch in half with the sticky side together; dispose of used patches in the trash out of reach from children and pets. Tablet should be swallowed whole and taken with a full glass of water. Abrupt disruption of high dosages may result in withdrawal effects including dizziness, headache, nausea, vomiting.
You Need to Avoid: Significant drug interactions exist, requiring dose/frequency adjustment or avoidance so avoid starting any new medications without consulting prescriber. Wash hands before and after applying the patch to avoid drug contact with eyes. Do not cut the patch. Once applied, do not remove the patch for 3 full days (motion sickness).
What should I watch for while using this medication?
Before starting Scopolamine, Transderm Scop/Buscopan make sure your physician is aware of any allergies or medications you currently take, if you have cardiovascular disease, a gastrointestinal obstruction, genitourinary disease/obstruction, glaucoma, hepatic impairment, a hiatal hernia, hyperthyroidism, psychosis, renal impairment, a seizure disorder, ulcerative colitis, are pregnant, or breastfeeding. Scopolamine, Transderm Scop/Buscopan use has been associated with rare but serious adverse events such as anaphylaxis, paradoxical bradycardia, CNS effects, idiosyncratic reaction, visual disturbances, and withdrawal effects.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Drowsiness, dizziness, xerostomia, agitation, confusion, visual impairment, mydriasis, pharyngitis
Note this is not a complete list of side effects, only the most common.
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