What is this medication?
Antiretroviral, Integrase Inhibitor (Anti-HIV)
How does this medication work?
Dolutegravir, Tivicay inhibits the strand transfer step of HIV-1 DNA integration by binding the integrase active site thereby inhibiting the HIV replication cycle.
How should I take this medication?
Oral: 50mg once or twice daily depending on regimen and patient status as this medication must be used in combination with other antiretroviral agents.
How to Take: Administer without regard to meals 2 hours before or 6 hours after cation-containing antacids or laxatives, sucralfate, oral supplements containing iron or calcium, or buffered medications. Dolutegravir and supplements containing calcium or iron can be taken together with food and an alternate method.
What should I watch for while using this medication?
Before starting Dolutegravir, Tivicay make sure your physician is aware of any allergies or medications you currently take, if you have liver disease, kidney disease, are pregnant, or breastfeeding. Dolutegravir, Tivicay use has been associated with rare but serious adverse events such as hepatotoxicity, hypersensitivity reactions, and immune reconstitution syndrome.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Increased serum lipase, hyperglycemia, insomnia, increased creatinine phosphokinase in blood specimen
Note this is not a complete list of side effects, only the most common.
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