What is this medication?
Second Generation (Atypical) Antipsychotic; Antimanic Agent
Risperidone/Risperdal is officially indicated for bipolar mania, irritability associated with autistic disorder, and schizophrenia. It is also prescribed off-label for severe acute agitation/aggression, bipolar disorder, delusional disorder, chorea related to Huntington disease, major depressive disorder, treatment resistant obsessive-compulsive disorder, or Tourette syndrome. (may be used for other conditions not listed)
“ALERT: US Boxed Warning
Increased mortality in elderly patients with dementia-related psychosis:
Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Risperidone is not approved for the treatment of patients with dementia-related psychosis and has not been studied in this population.”
How does this medication work?
Risperidone/Risperdal benzisoxazole antipsychotic that binds various neurotransmitter receptors in the brain such as serotonin (5-HT1A, 5-HT1C, 5-HT1D, 5-HT2), dopamine (D2, D1), histamine, and adrenergic (alpha1, alpha2). Does not affect muscarinic, beta1 or beta2 receptors. Has mixed effects at the various receptors (inhibits some and activates others). Brains response to altered chemistry results in desired effects.
How should I take this medication?
Oral: 0.25-16mg daily depending on what condition it is used for and patient response. In most cases doses over 8mg are avoided due to side effects.
How to Take: Follow instructions provided by physician/pharmacy label, take consistently at same times each day unless otherwise directed, store at room temperature
You Need to Avoid: Operating heavy machinery or driving at least until you know how the medication affects you. Do not stop this medication suddenly, make sure your physician is aware and can create a tapering schedule so you can come off slowly and prevent any withdrawal symptoms. This medication has many drug interactions so ask your pharmacist before starting any over the counter medications or supplements.
What should I watch for while using this medication?
Before starting Risperidone/Risperdal make sure your physician is aware of any allergies or medications you currently take, if you have kidney disease, liver disease, cardiovascular disease, a history of seizures or are pregnant or breastfeeding. Suicidal ideation is inherent with bipolar disorder or psychotic illness so caution must be used and any major changes in personality or mood should be reported to physician immediately.
This medication also required regular bloodwork and follow up with your physician to monitor for adverse reactions.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Hyperprolactinemia, weight gain, increased appetite, vomiting, constipation, upper abdominal pain, urinary incontinence, drowsiness, extra-pyramidal reaction, insomnia, headache, anxiety, drooling, tremor, nasopharyngitis, rhinorrhea, cough, fever, increased blood pressure, decreased HDL (good cholesterol), hyperglycemia, increased LDL (bad cholesterol).
Note- this is not a complete list of side effects, only common ones and are generally dosage dependent. When higher doses are required the physician has weighed the risks and found the benefits to be greater, however regular monitoring (blood sugar, cholesterol, blood pressure, etc.) is important to make sure this does not change. May rarely cause neuroleptic malignant syndrome.
- Choosing a selection results in a full page refresh.
- Press the space key then arrow keys to make a selection.