What is this medication?
Nabumetone, Relafen/Relafen DS
Analgesic, Nonsteroidal Anti-Inflammatory Drugs
Nabumetone, Relafen/Relafen DS is indicated for management of rheumatoid arthritis, osteoarthritis.
“Alert US Warning
FDA has issued a warning on the use of NSAIDs from 20 weeks gestation or later in pregnancy can lead to fetal renal dysfunction leading to oligohydramnios, neonatal renal impairment which may be fatal. NSAIDs cause an increased risk of cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. Nabumetone, Relafen/Relafen DS is contraindicated in coronary artery bypass graft (CABG) surgery. NSAIDs cause an increased risk of serious gastrointestinal adverse events such as bleeding, ulceration and perforation of the stomach or intestines, which can be fatal.”
How does this medication work?
Nabumetone, Relafen/Relafen DS is used to reduce pain, inflammation, and swelling by blocking the effect of natural substances called cyclo-oxygenase (COX) enzymes.
How should I take this medication?
Usual (Oral): 1000mg as a single dose; adjust dose based on clinical response up to a maximum of 2000mg daily in 1 to 2 divided doses.
How to Take: Take with food.
What should I watch for while using this medication?
Before starting Nabumetone, Relafen/Relafen DS make sure your physician is aware of any allergies or medications you currently take, and activities you perform. Nabumetone, Relafen/Relafen DS like other NSAIDs cause an increased risk of serious and potentially fatal cardiovascular thrombotic events, including myocardial infarction and stroke. Nabumetone, Relafen/Relafen DS can cause drug reactions characterized with eosinophilia and systemic symptoms. Nabumetone, Relafen/Relafen DS does increase the risk of serious gastrointestinal conditions such an ulceration, bleeding and perforation. Nabumetone, Relafen/Relafen DS has also been associated with decreased platelet adhesion and aggregation, hyperkalemia, photosensitivity, hepatic effects and potentially serious skin reactions including exfoliative dermatitis, Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN); may occur without warning. Nabumetone, Relafen/Relafen DS should be used with caution in patients with asthma, coronary artery bypass graft (CABG) surgery, hepatic and/or renal impairment.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Abdominal pain, diarrhea, dyspepsia, increased liver enzymes, edema, diaphoresis, pruritus, skin rash, constipation, flatulence, gastritis, nausea, occult blood in stools, stomatitis, vomiting, xerostomia, dizziness, drowsiness, fatigue, headache, insomnia, nervousness, tinnitus
Note: this is not a complete list of side effects, only the most common.
- Choosing a selection results in a full page refresh.
- Press the space key then arrow keys to make a selection.