What is this medication?
Misoprostol, Cytotec is indicated for prevention of drug-induced gastric ulcers, and termination of intrauterine pregnancy.
“Alert: US Warning
Misoprostol, Cytotec can birth defects, abortion, premature birth and/or uterine rupture when given to pregnant women. Patients must be advised of the abortifacient property and warned not to give the drug to others.”
How does this medication work?
Misoprostol, Cytotec is a prostaglandin E1 analog that binds to myometrial cells and induces uterine contractions. Misoprostol, Cytotec also replaces the protective prostaglandins consumed by prostaglandin-inhibiting therapies.
How should I take this medication?
Usual (Oral): 100mcg to 200mcg 4 times daily for prevention of drug-induced gastric ulcers.
Usual (Intravaginal): Insert 800mcg intravaginally, may repeat every 3 hours for 2 additional doses if needed.
How to Take: Take with food and avoid magnesium containing antacids to minimize diarrhea. f removing from the refrigerator, allow the solution to reach room temperature before administration. Infuse over at least 15 minutes. Flush the IV line with 10ml of normal saline following the infusion. Make sure to never infuse other medications using the same line. Patients must be appropriately hydrated prior to treatment.
What should I watch for while using this medication?
Before starting Misoprostol, Cytotec make sure your physician is aware of any allergies or medications you currently take, and current medical conditions. Women must be advised of the abortifacient property of misoprostol. Misoprostol, Cytotec should be used with caution in patients with cardiovascular disease and renal impairment.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Diarrhea, abdominal pain, headache, constipation, dyspepsia, flatulence, nausea, vomiting.
Note this is not a complete list of side effects, only the most common.
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