What is this medication?
Neomycin+Polymyxin B+Dexamethasone, Maxitrol
Indicated for treatment of inflammatory ocular conditions.
How does this medication work?
Neomycin+Polymyxin B+Dexamethasone, Maxitrol is used to treat eye conditions that involve inflammation and/or bacterial infections. Maxitrol contains neomycin and polymyxin b which interfere with bacterial protein synthesis causing bacterial cell death. Dexamethasone is a corticosteroid that decreases inflammation by suppression of neutrophil migration, decreased production of inflammatory mediators, and reversal of increased capillary permeability; suppresses normal immune response.
What should I watch for while using this medication?
Before using Neomycin+Polymyxin B+Dexamethasone, Maxitrol make sure your physician is aware of any allergies or medications you currently take, pre-existing medical conditions and activities you perform. Prolonged use of corticosteroids may increase the incidence of secondary ocular infections (including fungal infections). Acute purulent ocular infections may be masked or exacerbated with use. Fungal infection should be suspected in any patient with persistent corneal ulceration who has received corticosteroids. Neomycin may cause cutaneous sensitization. Prolonged use of corticosteroids may result in glaucoma; damage to the optic nerve, defects in visual acuity and fields of vision, corneal and scleral thinning (leading to perforation), and posterior subcapsular cataract formation may occur. Use following cataract surgery may delay healing or increase the incidence of bleb formation. Maxitrol should be used with caution in patients with glaucoma, and ocular herpes simplex.
How should I take this medication?
Suspension: Instill 1 to 2 drops into the conjunctival sac of the affected eye(s) 4 to 6 times daily. In severe disease, drops may be used hourly; frequency should decrease as signs and symptoms improve.
Ointment: Place ~1/2” ribbon in the conjunctival sac of the affected eye(s) 3 to 4 times daily
Note: If signs and symptoms do not improve after 2 days of treatment, the patient should be reevaluated.
How to Take:
Ointment: Apply into pocket between eyeball and lower lid; patient should look downward before closing eye. To avoid contamination, do not touch the tip of the tube to the eye or any other surface.
Suspension: Shake well before using. Tilt head back, instill suspension into the conjunctival sac, and close eye(s). Apply light finger pressure on the lacrimal sac for 1 minute following installation. To avoid contamination, do not touch the dropper to the eye or any other surface.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 20 to 25° C (68 to 77° F). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
The frequency and incidence of side effects is not well defined but do include:
Hypersensitivity reaction, secondary infection, glaucoma, increased intraocular pressure, optic nerve damage (infrequent), subcapsular posterior cataract, wound healing impairment.
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