What is this medication?
Indicated for treatment of bipolar disorder, focal (partial) onset seizures and generalized onset seizures.
“Alert: Black Box Warning
Serious skin rashes:
Lamotrigine can cause serious rashes requiring hospitalization and discontinuation of treatment. The incidence of these rashes, which have included Stevens-Johnson syndrome, is approximately 0.3% to 0.8% in pediatric patients (2 to 17 years of age) and 0.08% to 0.3% in adults receiving lamotrigine.”
How does this medication work?
The exact mechanism of action of Lamotrigine, Lamictal is not known. However, it has been shown to selectively bind to sodium channels and stabilize presynaptic neurons in addition to inhibiting glutamate release.
How should I take this medication?
Oral: 25mg to 600mg daily depending upon dosage form and indication.
How to Take:
Oral Chewable Tablet: May be chewed, dispersed in water, or diluted fruit juice, or swallowed whole. To disperse tablets, add to a small amount of liquid (just enough to cover tablet); let sit ~1 minute until dispersed; swirl solution and consume immediately. Do not administer partial amounts of liquid. If tablets are chewed, a small amount of water or diluted fruit juice should be used to aid in swallowing.
Orally Dissolving Tablet: Place tablets on tongue and move around in the mouth. Tablets will dissolve rapidly and can be swallowed with or without food or water.
Extended Release Tablet: Administer without regard to meals. Swallow whole; do not chew, crush, or cut.
What should I watch for while using this medication?
Before starting Lamotrigine, Lamictal make sure your physician is aware of any allergies and medications you currently take. There are a number of serious adverse reactions that can occur when taking Lamotrigine, Lamictal including aseptic meningitis, blood dyscrasias (i.e. neutropenia, leukopenia, thrombocytopenia, pancytopenia, anemia, and aplastic anemia), dizziness, drowsiness, multiorgan hypersensitivity and serious skin rashes.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Nausea, vomiting, constipation, dyspepsia, abdominal pain, anorexia, peptic ulcer, chest pain, edema, insomnia, drowsiness, fatigue, ataxia, pain, agitation, emotional lability, confusion, skin rash, increased libido, weight loss or gain, dysmenorrhea, urinary frequency, rectal hemorrhage, infection, muscle and joint pain, visual disturbances, rhinitis, cough, bronchitis, shortness of breath, infections.
Note this is not a complete list of side effects for Lamotrigine, Lamictal only common ones.
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