What is this medication?
Antiretroviral, Integrase Inhibitor (Anti-HIV) and Reverse Transcriptase Inhibitor (Anti-HIV)
Indicated for treatment of IV-1 Infection.
How does this medication work?
Dolutegravir is an integrase inhibitor that stops HIV integrase by binding to the integrase active site and prevents retroviral DNA integration.
Rilpivirine, a non-nucleoside reverse transcriptase inhibitor, that binds to reverse transcriptase and blocks the RNA-dependent and DNA-dependent polymerase activities, including HIV-1 replication.
How should I take this medication?
Usual (Oral): one tablet (50mg/25mg) once daily.
Note: Prior to switching to dolutegravir/rilpivirine, Juluca, patients must be virologically suppressed on a stable antiretroviral regimen for ≥6 months with no history of treatment failure and no known resistance to dolutegravir or rilpivirine.
How to Take: Take with a meal. Take 4 hours before or 6 hours after antiacids, sucralfate, iron or calcium containing supplements, or buffered medications.
What should I watch for while using this medication?
Before starting Dolutegravir and Rilpivirine, Juluca make sure your physician is aware of any allergies or medications you currently take, and current medical conditions. Dolutegravir and Rilpivirine, Juluca have caused changes in mood, depression, anxiety and suicidal ideation. Patients should always be monitored for severe depressive episodes while taking Dolutegravir and Rilpivirine, Juluca. Dolutegravir and Rilpivirine, Juluca can cause hepatotoxicity, hypersensitivity reactions resulting in organ dysfunction, lactic acidosis, and immune reconstitution syndrome. Dolutegravir and Rilpivirine, Juluca should not be used in patients with severe hepatic and renal impairment.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Headache, hyperglycemia, diarrhea, reduced bone mineral density.
Note this is not a complete list of side effects, only the most common.
- Choosing a selection results in a full page refresh.
- Press the space key then arrow keys to make a selection.