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What is this medication?

Irbesartan, Avapro
Angiotensin II Receptor Blocker; Antihypertensive

Irbesartan, Avapro is indicated for treatment of diabetic nephropathy, and hypertension.

“Alert: Black Box Warning

Fetal toxicity:
When pregnancy is detected, discontinue irbesartan as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus.”

How does this medication work? 

Irbesartan, Avapro is an angiotensin II blocker and prevents the angiotensin II from binding to its receptor.  Angiotensin II acts as a vasoconstrictor and stimulates the release of aldosterone. Once aldosterone is released, sodium as well as water are reabsorbed. The end result is an elevation in blood pressure. Irbesartan, Avapro thereby prevent vasoconstriction and the aldosterone secreting effects of angiotensin II.

How should I take this medication? 

Oral: 150mg to 300mg daily.

How to Take: Take with or without food.

What should I watch for while using this medication? 

Before starting Irbesartan, Avapro make sure your physician is aware of any allergies and medications you currently take.  There is a risk of developing hyperkalemia and worsening renal function when taking Irbesartan, Avapro so it is best advised that your doctor monitor you carefully for any complications 

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Hyperkalemia, dizziness, hypotension, fatigue, diarrhea, heartburn, and dyspepsia.

Note this is not a complete list of side effects, only common ones.