INLYTA (Axitinib)

INLYTA (Axitinib)

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PFIZER
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$1,399.99 USD
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$1,399.99 USD
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Shipped from Canada.

prescription

What is this medication?

Axitinib, Inlyta
Antineoplastic Agent, Tyrosine Kinase Inhibitor, Vascular Endothelial Growth Factor (VEGF) Inhibitor

Axitinib, Inlyta is indicated for treatment of renal cell carcinoma.

How does this medication work?

Axitinib, Inlyta is a tyrosine kinase inhibitor that inhibits vascular endothelial growth factor receptors (VEGF) inducing apoptosis of cancer cells and suppressing tumor growth, angiogenesis and metastasis.

How should I take this medication?

Renal cell carcinoma, first-line combination therapy:
In combination with Avelumab: Initial: 5 mg twice daily, every 12 hours. May increase to 7 mg twice daily and then 10 mg twice daily if initial 5 mg is well tolerated for 2 weeks or longer. Patient may also reduce to 3 mg twice daily and then 2 mg twice daily based on adverse events.

In combination with Pembrolizumab: Initial: 5 mg twice daily, every 12 hours. May increase to 7 mg twice daily and then 10 mg twice daily if initial 5 mg is well tolerated for 6 weeks or longer. Patient may also reduce to 3 mg twice daily and then 2 mg twice daily based on adverse events.

Renal cell carcinoma, second-line single-agent therapy:
Initial (Oral): 5 mg twice daily, every 12 hours. May increase to 7 mg twice daily and then 10 mg twice daily if initial 5 mg is well tolerated for 2 weeks or longer. Patient may also reduce to 3 mg twice daily and then 2 mg twice daily based on adverse events.

How to Take: Oral: Swallow tablet(s) whole with a full glass of water. May administer with or without food.

You Need to Avoid: Do not crush, split, or chew dosage form.

What should I watch for while using this medication?

Before starting Axitinib, Inlyta make sure your physician is aware of any allergies or medications you currently take, if you are pregnant, or breastfeeding. Axitinib, Inlyta use has been associated with rare but serious adverse events such as cardiotoxicity, GI perforation/fistula, hemorrhage, hepatotoxicity, hypertension, posterior reversible encephalopathy syndrome, proteinuria, thrombotic events, thyroid disorders, and wound healing complications.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible.  However, if it is almost time for your next dose, take only that scheduled dose.  Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times.  Store at room temperature, 59 to 86° F (15 to 30° C).  Protect from light.  Keep the container tightly closed.  Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

Hypertension, Palmar-plantar erythrodysesthesia, skin rash, decreased serum bicarbonate, hyperglycemia, hyperkalemia, hypernatremia, hypoalbuminemia, hypocalcemia, hypoglycemia, hyponatremia, hypophosphatemia, hypothyroidism, weight loss, abdominal pain, constipation, decreased appetite, diarrhea, dysgeusia, increased serum amylase, increased serum lipase, mucosal swelling, nausea, stomatitis, vomiting, proteinuria, decreased absolute lymphocyte count, decreased platelet count, decreased white blood cell count, hemorrhage, increased serum alanine aminotransferase, increased serum alkaline phosphatase, increased serum aspartate aminotransferase, fatigue, headache, voice disorder, arthralgia, asthenia, limb pain, increased serum creatinine, cough, dyspnea, pruritusxeroderma, dyspepsia, upper abdominal pain, increased hemoglobin, myalgia, dizziness

Note this is not a complete list of side effects, only the most common.