What is this medication?
Antidiabetic Agent, Dipeptidyl Peptidase 4 (DPP-4) Inhibitor; Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor
Empagliflozin+Linagliptin, Glyxambi is indicated for treatment of diabetes mellitus, type 2
How does this medication work?
Glyxambi is an antidiabetic drug that combines empagliflozin and Linagliptin. Empagliflozin inhibits sodium-glucose cotransporter 2 (SGLT2) in the proximal renal tubules, reduces reabsorption of filtered glucose resulting in an increased urinary excretion of glucose, thereby lowering blood glucose levels. Linagliptin inhibits dipeptidyl peptidase 4 (DPP-4) enzyme resulting in prolonged active incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) regulating glucose level by increasing insulin synthesis and secretion while decreasing glucagon secretion.
How should I take this medication?
Usual (Oral): Take one tablet (empagliflozin 10mg/linagliptin 5mg) once daily; may increase to (empagliflozin 25mg/linagliptin 5mg) once daily.
How to Take: Take one tablet once daily in the morning with or without food.
What should I watch for while using this medication?
Before starting Empagliflozin+Linagliptin, Glyxambi make sure your physician is aware of any allergies or medications you currently take, and activities you perform. Empagliflozin+Linagliptin, Glyxambi has been reported to cause arthralgia, bone fractures, genital infections, ketoacidosis, hypotension, necrotizing fasciitis, pancreatitis, renal effects, and urinary tract infections.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Urinary tract infection, hypoglycemia, upper respiratory tract infection, nasopharyngitis
Note this is not a complete list of side effects, only the most common.
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