What is this medication?
Tiagabine, Gabitril is indicated for treatment of focal (partial) seizures.
How does this medication work?
The exact mechanism by which Tiagabine, Gabitril exerts anti seizure activity is not definitively known; but it is thought that Tiagabine, Gabitril enhances the activity of gamma aminobutyric acid (GABA). It is thought that the binding of Tiagabine, Gabitril to the GABA uptake carrier inhibits the uptake of GABA into presynaptic neurons, allowing an increased amount of GABA to be available to postsynaptic neurons.
How should I take this medication?
Oral: Take 4mg once daily and increase the dose by 4mg to 8mg based on clinical response. Doses up to 56mg daily need to be divided into 2 to 4 divided doses.
Note: Do not use a loading dose, rapid titration, and/or increases with large dose increments.
How to Take: Administer with food
What should I watch for while using this medication?
Before using Tiagabine, Gabitril, speak with your doctor about your medical history, especially if you have liver disease. Tiagabine, Gabitril can cause CNs depression, which may impair physical and/or mental functioning and should be used with caution in patients that perform tasks that require mental alertness. Tiagabine, Gabitril has caused severe reactions, including Steven Johnson syndrome that have caused death. Moderately severe to incapacitating weakness has been reported with Tiagabine, Gabitril. Monitor for any changes in mood and/or behavior and notify your doctor immediately if you experience depression and/or suicidal thoughts.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Dizziness, drowsiness, nervousness, lack of concentration, nausea, infection, insomnia, stomach pain, diarrhea, vomiting, fatigue, flu-like symptoms, tremor, and muscle weakness, urinary tract infection, myalgia, amblyopia, nystagmus, pharyngitis, and increased cough.
Note this is not a complete list of side effects, only the most common.
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