What is this medication?
Alendronate+Cholecalciferol, Fosamax Plus D(US)/Fosavance(CDN)
Bisphosphonate, Vitamin D Analog
Brand Name US: Fosamax Plus D
Canadian Equivalent: Fosavance
Indicated for treatment of osteoporosis.
Limitations of use: Not for use in the treatment of vitamin D deficiency.
How does this medication work?
Alendronate is a bisphosphonate that inhibits osteoclasts and slows down bone resorption allowing osteoblasts to work more effectively to build bone mass.
Cholecalciferol is a fat-soluble vitamin that helps the body absorb calcium and phosphorus increasing bone mineralization.
How should I take this medication?
Usual (Oral): one tablet (alendronate 70mg/cholecalciferol 2800 units or 5600 units) once weekly.
Note: Patients should receive supplemental calcium if dietary intake is inadequate. Some patients may require additional vitamin D while taking this product (not intended to treat vitamin D deficiency).
How to Take: Take in the morning at least 30 minutes before breakfast, with a full glass of water. Swallow whole; do not chew or crush the tablet. Do not lie down for ≥30 minutes and until after first food of the day (to reduce esophageal irritation).
What should I watch for while using this medication?
Before starting Alendronate+Cholecalciferol, Fosamax Plus D/Fosamax make sure your physician is aware of any allergies or medications you currently take, and current medical conditions. Atypical femur fractures, severe joint and bone pain, gastrointestinal irritation, ocular effects and osteonecrosis of the jaw can occur when taking Alendronate+Cholecalciferol. Alendronate+Cholecalciferol, Fosamax Plus D/Fosamax should be used with caution in patients with hypercalcemia and/or hypercalciuria, undergoing bariatric surgery, and renal impairment.
What if I miss a dose?
If a once-weekly dose is missed, administer the next morning after remembered. Then return to the original scheduled day of the week on the once-weekly schedule; however, do not administer 2 doses on the same day.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
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