What is this medication?
Antineoplastic Agent, Aromatase Inhibitor
Indicated for treatment of breast cancer.
How does this medication work?
Exemestane/Aromasin is an irreversible, steroidal aromatase inactivator. It is structurally related to androstenedione and is converted to an intermediate that irreversibly blocks the active site of the aromatase enzyme, leading to inactivation (“suicide inhibition”) and thus preventing conversion of androgens to estrogens in peripheral tissues. Exemestane/Aromasin significantly lowers circulating estrogens in postmenopausal breast cancers where growth is estrogen-dependent.
How should I take this medication?
Oral: 25mg once daily.
How to Take: Take after a meal.
What should I watch for while using this medication?
Before starting Exemestane/Aromasin make sure your physician is aware of any allergies or medications you currently take. Exemestane/Aromasin can cause a decrease in bone mineral density due to a decrease in circulating estrogen levels, lymphopenia and elevated liver enzymes. Exemestane/Aromasin should not be used in premenopausal women.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
The frequency of side effects is not well defined but has been reported to include the following:
Hypertension, edema, ischemic heart disease, angina pectoris, myocardial infarction, fatigue, insomnia, pain, headache, depression, dizziness, anxiety, paresthesia, confusion, hypoesthesia, hyperhidrosis, alopecia, dermatitis, pruritis, skin rash, hot flashes, weight gain, nausea, abdominal pain, diarrhea, vomiting, constipation, dyspepsia, urinary tract infection, lymphedema, elevated liver enzymes, infection, joint and muscle pain, weakness, osteoporosis, fracture, muscle cramps, visual disturbance, dyspnea, cough, bronchitis, pharyngitis, rhinitis, sinusitis, upper respiratory tract infection, fever.
Note this is not a complete list of side effects for Exemestane/Aromasin only common ones.
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