What is this medication?
Antacid, Proton Pump Inhibitor
Esomeprazole/Nexium is officially indicated for erosive esophagitis, duodenal/gastric ulcer, gastroesophageal reflux disease (GERD), or Helicobacter pylori eradication. It is also commonly prescribed off-label for Barrett esophagus, dyspepsia, or NSAID-induced ulcer prevention. (may also be used for conditions not listed)
How does this medication work?
Esomeprazole/Nexium inhibits the H+/K+ ATP pump (proton pump) in stomach parietal cells which are the cells that produce stomach acid thereby reducing its production. Esomeprazole is the more active S-isomer of omeprazole.
How should I take this medication?
Oral: 20mg-40mg once or twice daily
How to Take: Follow instructions provided by physician/pharmacy label, swallow whole, take consistently at same times each day usually 30- 60minutes before a meal unless otherwise directed, store at room temperature.
You Need to Avoid: Do not stop this medication quickly as your body has gotten used to it. Slowly reduce the dose to prevent rebound symptoms. Many people who stop this medication without dosage reduction become symptomatic even though their original condition may be resolved.
What should I watch for while using this medication?
Before starting Esomeprazole/Nexium make sure your physician is aware of any allergies or medications you currently take, if you have liver disease, or are pregnant or breastfeeding. This medication may mask a more serious condition so regular follow up which physician is recommended if required for long periods of time. Long term use may also be associated with decreased bone density due to decreased calcium absorption, low b12 due to decreased absorption and increased risk of intestinal infection as stomach acid can act as a defence against certain infectious agents.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Side effects are uncommon with this medication however some that may occur are headache, diarrhea, abdominal pain, and vomiting, most of which tend to happen in children over adults.
Note this is not a complete list but the most common that can occur
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