What is this medication?
Aclidinium+Formoterol, Duaklir Pressair (US)/Duaklir Genuair (Canada)
Anticholinergic, Beta agonist, long- acting, inhalant (oral)
Brand Name US: Duaklir Pressair
Canadian Equivalent: Duaklir Genuair
Indicated for treatment of chronic obstructive pulmonary disease (COPD).
How does this medication work?
Aclidinium is an anticholinergic agent that is a reversible competitive inhibitor of type 3 muscarinic (M3) receptors which causes the smooth muscle in the bronchi to relax and subsequently leads to bronchodilation.
Formoterol is a selective beta agonist that binds to beta2 receptors located on the bronchial smooth muscle causing the airway to dilate reducing the work required to breath while having little effect on heart rate.
What should I watch for while using this medication?
Before starting Aclidinium+Formoterol, Duaklir Pressair/Duaklir Genuair make sure your physician is aware of any allergies or medications you currently take. Hyperthyroidism, cardiovascular disease, electrolyte disturbances, urinary retention and rare paradoxical cases of life-threatening bronchospasm have been reported.
How should I take this medication?
Oral Inhalation: Dry Powder inhaler
Take one inhalation twice daily.
How to Take: The inhaler is breath actuated; administer via oral inhalation once in the morning and evening. Remove inhaler from sealed bag immediately prior to first use. To load dose, remove protective cap and press the orange button all the way down (avoid tilting inhaler). If the control window is green, the inhaler is ready for use; if the control window is red, reactivate inhaler again by pressing and releasing the orange button. Prior to inhaling the dose, exhale fully (do not exhale into the inhaler), then close lips tightly around the inhaler mouthpiece and inhale (rapidly, steadily, and deeply); do not hold the orange button down while inhaling. Keep breathing in even after a “click” is heard to ensure that the full dose has been given. Ensure the dose was delivered correctly by observing the control window change from green to red; if the control window is still green, repeat inhalation steps. When control window has been verified as red, replace the protective cap until next use. Refer to product labeling for additional administration instructions.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature between 15°C and 30°C protected from heat and moisture.
Do not wash or put inhaler in water; mouthpiece may be cleaned with a dry tissue or cloth. Discard the inhaler when the dose counter displays “0” or within 60 days after removal from sealed bag (whichever occurs first).
What are the possible side effects of using this medication?
Headache, dizziness, insomnia, urinary tract infection, muscle and joint pain, cough, and sinusitis.
Note this is not a complete list of side effects, only common ones.
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