CYCLOMEN (Danazol)
CYCLOMEN (Danazol)
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CYCLOMEN (Danazol)

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$144.99 USD
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$144.99 USD
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Shipped from Canada.


What is this medication?

Danazol, Cyclomen

Danazol, Cyclomen is indicated for treatment of endometriosis, hereditary angioedema prophylaxis.

“Alert: Black Box Warning

Thromboembolic Events
Thromboembolism, thrombotic and thrombophlebitic events, including sagittal sinus thrombosis and life-threatening or fatal strokes have been reported.

Use of Danazol, Cyclomen in pregnancy is contraindicated. An additional form of contraception such as a barrier non-hormonal method should be used in all women capable of becoming pregnant during therapy.  Additionally, a nonhormonal method of contraception should be used during therapy.  Exposure to Danazol, Cyclomen

in utero may result in androgenic effects on the female fetus; reports of clitoral hypertrophy, labial fusion, urogenital sinus defect, vaginal atresia, and ambiguous genitalia have been received.

Hepatic effects
Peliosis hepatis and benign hepatic adenoma have been observed with long-term use of Danazol, Cyclomen. 

Intracranial hypertension
Danazol, Cyclomen has been associated with several cases of benign intracranial hypertension also known as pseudotumor cerebri. Early signs and symptoms of benign intracranial hypertension include papilledema, headache, nausea and vomiting, and visual disturbances.”

How does this medication work? 

Danazol, Cyclomen suppresses pituitary output of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), resulting in regression and atrophy of normal and ectopic endometrial tissue; decreases rate of growth of abnormal breast tissue; reduces attacks associated with hereditary angioedema by increasing levels of C4 component of complement

How should I take this medication? 

Oral: 200mg to 800mg daily.

How to Take:
Initiate therapy during menstruation or ensure patient is not pregnant while on therapy.

What should I watch for while using this medication? 

Before starting Danazol, Cyclomen make sure your physician is aware of any allergies or medications you currently take.  Danazol, Cyclomen may cause non-reversible androgen side effects, hepatotoxicity, intracranial hypertension and thromboembolic events.  Danazol, Cyclomen should be used with caution in patients who may have cyclic breast pain, diabetes, edematous conditions (i.e. cardiovascular disease, migraine, seizure disorder, renal impairment) and porphyria.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

The frequency of side effects has not been reported but do include the following: 

Acute myocardial infarction, edema, flushing, hypertension, palpitations, syncope, tachycardia, acne vulgaris, alopecia, diaphoresis, maculopapular rash, papular rash, pruritus, seborrhea, urticaria, vesicular eruption, aenorrhea (may continue post-therapy), change in libido, decreased glucose tolerance (and glucagon changes), decreased HDL cholesterol, decreased thyroxine binding globulin, hirsutism (mild), increased LDL cholesterol, increased thyroxine binding globulin, menstrual disease (altered timing of cycle, spotting), weight gain, constipation, gastroenteritis, nausea, vomiting, asthenospermia, breast atrophy, decreased ejaculate volume, hematuria, inhibition of spermatogenesis, spermatozoa disorder (changes in sperm count and semen viscosity), vaginal dryness, vaginal irritation, hematologic disturbances (i.e. anormal erythrocytes (increased), decreased sex hormone binding globulin, eosinophilia, increased sex hormone-binding globulin, leukocytosis, leukopenia, malignant neoplasm (after prolonged use), petechial rash, polycythemia, purpuric rash, thrombocythemia, thrombocytopenia), cholestatic jaundice, hepatic adenoma, hepatic neoplasm (malignant; after prolonged use), increased liver enzymes, jaundice, peliosis hepatitis, depression, dizziness, emotional lability, fatigue, headache, nervousness, paresthesia, sleep disorder, voice disorder (deepening of the voice, hoarseness, instability, sore throat, ankylosing spondylitis, arthralgia, asthenia, back pain, increased creatine phosphokinase in blood specimen, joint swelling, limb pain, muscle cramps, muscle spasm, neck pain, tremor, visual disturbance.

Note this is not a complete list of side effects for Danazol, Cyclomen only common ones.