What is this medication?
Anti-interleukin 17A Monoclonal Antibody; Antipsoriatic Agent; Monoclonal Antibody
Ankylosing spondylitis, axial spondyloarthritis, plaque psoriasis, psoriatic arthritis.
How does this medication work?
Secukinumab, Cosentyx is a humanized IgG1 monoclonal antibody that selectively binds to the interleukin-17A (IL-17A) cytokine and inhibits its interaction with the IL-17 receptor. IL-17A is a naturally occurring cytokine involved in normal inflammatory and immune responses. Secukinumab inhibits the release of proinflammatory cytokines and chemokines.
How should I take this medication?
Loading Dose: Inject 150mg subcutaneously weekly
Without Loading Dose: Inject 300mg subcutaneously weekly
How to Take: Inject into the front of thighs, lower abdomen (≥2 inches away from the navel) or outer upper arms; administer each injection at a different anatomic location than a previous injection and avoid areas where the skin is tender, bruised, erythematous, indurated, or affected by psoriasis, or where there are scars or stretch marks. The Sensoready pen or prefilled syringe may be self-injected by the patient following proper training in SubQ injection technique; the lyophilized powder is to be administered by health care providers only.
The 300 mg dose should be divided into two 150 mg SubQ injections.
What should I watch for while using this medication?
Before starting make sure your physician is aware of any allergies or medications you currently take, you may be at an increased risk to infections and tuberculosis. There has also been reports of exacerbations of inflammatory bowel disease in at risk patients.
What if I miss a dose?
If you miss a dose, take it as soon as you remember. However, do not double up on your doses to make up for the missed dose. So, iIf it’s almost time to take your next dose, talk with your doctor or pharmacist. They can recommend when you should take your next dose.
How should I store this medication?
Store in the refrigerator at 2ºC to 8ºC (36ºF to 46ºF). Keep the product in the original carton until the time of use. Do not shake. Do not freeze.
Allow the reconstituted solution to reach room temperature (15 to 30 minutes) before administration. Secukinumab, Cosentyx does not contain preservatives; therefore, administer within 1 hour after removal from 2ºC to 8ºC (36ºF to 46ºF) storage.
What are the possible side effects of using this medication?
Infection and nasopharyngitis.
Note this is not a complete list of side effects for Secukinumab, Cosentyx only common ones.
- Choosing a selection results in a full page refresh.
- Press the space key then arrow keys to make a selection.