What is this medication?
Anticonvulsant, Triazole Derivative
Rufinamide, Banzel is indicated for treatment of Lennox-Gastaut syndrome.
How does this medication work?
Rufinamide, Banzel is a triazole-derivative antiepileptic whose exact mechanism is unknown. It prolongs the inactive state of the sodium channels, thereby limiting repetitive firing of sodium-dependent action potentials mediating anticonvulsant effects in vitro.
How should I take this medication?
Oral: 400 – 3200 mg daily in 2 equally divided doses
How to Take: Administer with food. Tablets may be swallowed whole, split in half, or crushed. Oral suspension should be administered using the provided adapter and calibrated oral syringe; shake well before each dose.
You Need to Avoid: Significant drug interactions exist, requiring dose/frequency adjustment or avoidance so avoid starting any new medications without consulting prescriber. Anticonvulsants should not be discontinued abruptly because of the possibility of increasing seizure frequency. Therapy should be withdrawn gradually to minimize the potential of increased seizure frequency unless safety concerns require a more rapid withdrawal.
What should I watch for while using this medication?
Before starting Rufinamide, Banzel make sure your physician is aware of any allergies or medications you currently take, if you have familial short QT syndrome, hepatic impairment, are pregnant, or breastfeeding. Rufinamide, Banzel use has been associated with rare but serious adverse events such as altered cardiac conduction, CNS effects, multiorgan hypersensitivity reactions, dermatologic reactions, leukopenia, and suicidal ideation.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Shortened QT interval, headache, drowsiness, dizziness, fatigue, nausea, vomiting, ataxia, decreased appetite, tremor, diplopia, blurred vision, nystagmus
Note this is not a complete list of side effects, only the most common
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