What is this medication?
Skeletal Muscle Relaxant
Baclofen (Oral) is indicated for treatment of spasticity.
How does this medication work?
Baclofen is a skeletal muscle relaxant that activates the GABAB receptor, which inhibits the transmission of mono-and-polysynaptic reflexes at the spinal cord level, possibly by hyperpolarization of primary afferent fiber terminals, with resultant relief of muscle spasticity.
How should I take this medication?
Usual (Oral): Oral: Initial: 5 mg 3 times daily; may increase dose after 3 to 5 days based on response and tolerability to 10 mg 3 times daily; may increase further as needed to a maximum dose of 60 mg/day in divided doses
How to Use: Administer without regard to meals.
What should I watch for while using this medication?
Before using Baclofen make sure your physician is aware of any allergies or medications you currently take, pre-existing medical conditions and activities you perform. Baclofen may cause urinary retention and should be used with caution in patients with urinary obstruction. Use Baclofen with caution in patients with a history of autonomic dysreflexia; presence of nociceptive stimuli or abrupt baclofen withdrawal may cause autonomic dysreflexia. Baclofen should also be used with caution in patients with peptic ulcer disease, decreased GI motility, and/or GI obstructive disorders. Patients with psychotic disorders, schizophrenia, or confusional states; may experience an exacerbation of their condition when using Baclofen. Baclofen should be used cautiously in patients with renal impairment, respiratory disease, seizure disorder.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Nausea, vomiting, confusion, dizziness, drowsiness, headache, hypotonia, asthenia, hypotension, peripheral edema, pruritus, urticaria, constipation, diarrhea, sialorrhea, xerostomia, difficulty in micturition, impotence, urinary frequency, urinary incontinence, urinary retention, depression, fatigue, insomnia, pain, paresthesia, seizure, speech disturbance, hypoventilation
Note this is not a complete list of side effects, only the most common.
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