APTIVUS (Tipranavir)

APTIVUS (Tipranavir)

Vendor
BOEHRINGER INGELHEIM
Regular price
$1,399.99 USD
Sale price
$1,399.99 USD
Regular price
Sold out
Unit price
per 

Shipped from Canada.

prescription

What is this medication? 

Tipranavir, Aptivus
Antiretroviral, Protease Inhibitor (Anti-HIV)

Indicated for treatment of HIV-1 infection.

“ALERT: US Boxed Warning

Hepatotoxicity:
Clinical hepatitis and hepatic decompensation, including some fatalities, have been reported. Extra vigilance is warranted in patients with chronic hepatitis B or hepatitis C coinfection, as these patients have an increased risk of hepatotoxicity.

Intracranial hemorrhage:
Both fatal and nonfatal intracranial hemorrhage have been reported.”

How does this medication work? 

Tipranavir, Aptivus binds to HIV-1 protease and inhibits cleavage of viral Gag-Pol polyprotein precursors into individual functional proteins required for infectious HIV. This results in the formation of immature, noninfectious viral particles.

How should I take this medication? 

Oral: 500 mg twice daily

How to Take: Swallow tipranavir capsules whole; do not open or chew. Tipranavir must be coadministered with ritonavir.  When using with ritonavir tablets, administer with food. When using with ritonavir capsules or solution, administer without regard to meals. Capsule contains dehydrated ethanol. Oral solution formulation contains vitamin E; additional vitamin E supplements should be avoided. Tipranavir is no longer recommended for use in the initial treatment of HIV. 

You Need to Avoid:  Significant drug interactions exist, requiring dose/frequency adjustment or avoidance so avoid starting any new medications without consulting prescriber.

What should I watch for while using this medication? 

Before starting Tipranavir, Aptivus make sure your physician is aware of any allergies or medications you currently take, if you have diabetes, hemophilia A/B, hepatic impairment, are high risk for bleeding, are pregnant, or breastfeeding. Tipranavir, Aptivus use has been associated with rare but potentially serious adverse events such as fat redistribution, hepatotoxicity, hyperlipidemia, immune reconstitution syndrome, intracranial hemorrhage, skin reactions, and sulfonamide allergy cross sensitivity.

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Prior to opening bottles of capsules, store at 2°C to 8°C (36°F to 46°F). After bottle is opened, may be stored at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F) for up to 60 days. For the oral solution store at 15°C to 25°C (59°F to 77°F). After bottle is open, use within 60 days. Do not refrigerate or freeze.

What are the possible side effects of using this medication? 

Skin rash, hypertriglyceridemia, hypercholesterolemia, diarrhea, increased serum transaminases, increased creatine phosphokinase,

Note this is not a complete list of side effects, only the most common