What is this medication?
Potassium Channel Blocker
Brand Name US: Ampyra
Canadian Equivalent: Fampyra
Dalfampridine, Ampyra/Fampyra is indicated to improve walking in patients with multiple sclerosis (MS)
How does this medication work?
Dalfampridine, Ampyra/Fampyra is a potassium channel blocker which improves conduction in focally demyelinated axons by delaying repolarization and prolonging the duration of action potentials. Enhanced neuronal conduction is thought to strengthen skeletal muscle fiber twitch activity, thereby, improving peripheral motor neurologic function.
How should I take this medication?
Oral: 10mg every 12 hours.
How to Take: Take with or without food. Do not chew, crush, dissolve, or divide tablet.
What should I watch for while using this medication?
Before starting Dalfampridine, Ampyra/Fampyra make sure your physician is aware of any allergies or medications you currently take. Dalfampridine, Ampyra/Fampyra is generally well tolerated; however there are a few risks to take into consideration. Seizures may occur within days to weeks after treatment initiation and have been reported more frequently in patients with no history of seizures. Discontinue use and do not reinitiate therapy if seizure occurs during treatment. Use Dalfampridine, Ampyra/Fampyra with caution in patients with renal impairment because of the higher risk of seizure and other adverse events, primarily neurologic effects, due to increased serum concentrations.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Urinary tract infection, insomnia, dizziness, headache, paresthesia, weakness, back pain, nasopharyngitis, pharyngolaryngeal pain.
Note this is not a complete list of side effects for Dalfampridine, Ampyra/Fampyra only common ones.
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