What is this medication?
Inhaled corticosteroid; Long acting Beta 2 Adrenergic Agonist
Fluticasone+Salmeterol, Advair/AirDuo/Wixela is indicated for asthma and chronic obstructive pulmonary disease (may also be used for conditions not listed)
How does this medication work?
Salmeterol relaxes the smooth muscle in the bronchioles via the beta2-adrenergic receptor. Fluticasone may reduce the formation, release, and activity of inflammatory mediators such as kinins, histamine and prostaglandins. It reduces cell migration to the affected area and reverses the dilation and blood vessel permeability result in decreased access of cells to the site.
What should I watch for while using this medication?
Before starting Fluticasone+Salmeterol, Advair/AirDuo/Wixela make sure your physician is aware of any allergies (lactose- note that this is for true allergy, not dietary lactose intolerance which is from a lack of lactase), medications you currently take, if you have cardiovascular disease, diabetes, liver disease, have hypokalemia, are pregnant, or breastfeeding
How should I take this medication?
Generally dosed twice daily, with the salmeterol component determining maximum dosage (50mcg twice a day) regardless of the inhaler design. The strength of the steroid component is determined by severity of symptoms and patient response. If the steroid component must be increased, then another formulation with more steroid may be used or an additional single entity steroid inhaler may be added.
How to Take: Follow instructions provided by physician/pharmacy label, take consistently at same times each day, store at room temperature. Follow priming instructions for the product received and make sure the pharmacist teaches you proper use/care of the device as there are various styles of inhaler available containing this combination. Rinse mouth with water and spit out after every use of medication to reduce risk of oral thrush.
You Need to Avoid: Do not exceed recommended dosages to avoid adverse reactions
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep this and all medication out of the reach of children. Store at 20° to 25°C (68° to 77°F). Store in a dry place away from direct heat and sunlight.
What are the possible side effects of using this medication?
Headache, upper respiratory tract infection, pneumonia, pharyngitis
Note this is not a complete list of side effects, only the most common ones.
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