ACZONE (Dapsone)

What is this medication?

Dapsone, Aczone
Topical Acne Product

Officially indicated for the treatment of acne vulgaris.

How does this medication work? 

Dapsone/Aczone possesses anti-inflammatory and antioxidant properties.  The mechanism of action on how dapsone/Aczone treats acne vulgaris is not known.

How should I take this medication? 

Acne Vulgaris
Topical: Apply a pea-sized amount of gel in a thin layer over the affected area once to twice daily.  If no improvement after 12 weeks of therapy, consult with a medical doctor.

How to Use Dapsone (Topical), Aczone:  Clean the skin before applying dapsone/Aczone and rub the gel into the affected area.  Avoid applying to your mouth, nose, eyes, mucous membrane, and/or broken skin.

What should I watch for while using this medication? 

Can cause localized discoloration of the skin and facial hair if benzoyl peroxide is used subsequently.

Avoid using in patients with congenital or idiopathic methemoglobinemia 

What if I miss a dose?

If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.

How should I store this medication?

Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Properly dispose of any unused medication after the expiration date.

What are the possible side effects of using this medication?

The frequency of side effects has not been reported.  However, the most common side effects associated with using Aczone/Dapsone are the following:

1% to 10%:

Respiratory: Sinusitis (2%)

Frequency not defined:

Central nervous system: Attempted suicide, tonic-clonic movements

Gastrointestinal: Abdominal pain, pancreatitis, severe vomiting

Respiratory: Pharyngitis