What is this medication?
Acetretin is indicated for treatment of severe psoriasis in adults
“Alert: Black Box Warning
Acetretin, Soritane has been linked to cause fetal abnormalities. Acetretin, Soritane should not be used by females who are pregnant, or who intend to become pregnant during therapy or at any time for at least 3 years following discontinuation of therapy. Acitretin, Soritane should be considered only for women with severe psoriasis unresponsive to other therapies or whose clinical condition contraindicates the use of other treatments. Females of reproductive potential must not be given a prescription for acitretin until pregnancy is excluded. “
How does this medication work?
Acitretin, Soriatane works by inhibiting the excessive cell growth and keratinisation (process by which skin cells become thickened due to the deposition of a protein within them) seen in psoriasis. It therefore reduces the thickening of the skin, plaque formation and scaling.
How should I take this medication?
Oral: 25mg to 50mg daily.
How to Take: Take with the main meal of the day.
What should I watch for while using this medication?
Before starting Acitretin, Soriatane make sure your physician is aware of any allergies or medications you currently take. Firstly, pregnancy needs to be excluded prior to starting treatment with Acitretin, Soriatane. Acetretin, Soriatane use has been shown to cause capillary leak syndrome, depression, exfoliative dermatitis, hepatotoxicity, abnormal lipid levels, tinnitus, photosensitivity, pseudotumor cerebri, skeletal abnormalities and visual disturbances. Consider therapy discontinuation and further evaluation if clinically indicated.
What if I miss a dose?
If you miss a dose of medication, try to take it as soon as possible. However, if it is almost time for your next dose, take only that scheduled dose. Do not take double or extra doses.
How should I store this medication?
Keep out of the reach of children at all times. Store at room temperature, 59 to 86° F (15 to 30° C). Protect from light. Keep the container tightly closed. Properly dispose of any unused medication after the expiration date.
What are the possible side effects of using this medication?
Hyperesthesia, paresthesia, rigors, cheilitis, alopecia, exfoliation of skin, xeroderma, nail disease, pruritis, skin rash, skin atrophy, hypertriglyceridemia, decreased HDL cholesterol, hypercholesterolemia, elevated liver enzymes, electrolyte disturbances, hematuria, leukocyturia, reticulocytosis, joint pain, spinal hyperostosis, dry eyes, rhinitis, epistaxis.
Note this is not a complete list of side effects for Acitretin, Soriatane only common ones.
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